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Article

Integrated study of copy number states and genotype calls using high-density SNP arrays.

Nucleic acids research - 1 Sept 2009

Sun Wei, Wright Fred A, Tang Zhengzheng, Nordgard Silje H, Van Loo Peter, Yu Tianwei, Kristensen Vessela N, Perou Charles M

Abstract excerpt

We propose a statistical framework, named genoCN, to simultaneously dissect copy number states and genotypes using high-density SNP (single nucleotide polymorphism) arrays. There are at least two types of genomic DNA copy number differences: copy number variations (CNVs) and copy number aberrations (CNAs). While CNVs are naturally occurring and inheritable, CNAs are acquired somatic alterations most often...

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Identifiers

PMID: 19581427
DOI: 10.1093/nar/gkp493
PMCID: PMC2935461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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