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Article

Production-scale purification of the recombinant major house dust mite allergen Der f 2 mutant C8/119S.

Journal of bioscience and bioengineering - 1 Nov 2010

Koyanagi Satoshi, Murakami Toshio, Maeda Toshihiro, Kawatsu Kenjirou, Okamura Hiroshi, Oda Yoshiaki, Miyatsu Yoshinobu, Sugawara Keishin, Mizokami Hiroshi

Abstract excerpt

A WHO position paper states that allergen immunotherapy is an effective treatment for allergic diseases, and well characterized allergens should be used in immunotherapy. The house dust mite is a major cause of allergic disease. However, the biological activity of the mite extracts currently used cannot be clearly determined, since these extracts contain various impurities. The use of recombinant allergens can...

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Identifiers

PMID: 20547344
DOI: 10.1016/j.jbiosc.2010.05.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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