Article
Comparison of skin prick test with serially diluted wild-type and genetically engineered recombinant Der f2.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Mar 2000
Kusunoki T, Inoue Y, Korematsu S, Harazaki M, Yokota T, Hosoi S
Abstract excerpt
BACKGROUND: C8/119S, a genetically engineered less allergenic mutant of group II allergen (Der f2) of house dust mite, Dermatophagoidesfarinae, was constructed in order to reduce the risk of anaphylactic reactions of allergen specific immunotherapy. OBJECTIVE: To further evaluate, with a larger number of mite-allergic patients, the safety of C8/119S for the treatments of humans. METHOD: We tested the...
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