Article
Recombinant allergens for analysing T-cell responses.
Methods (San Diego, Calif.) - 1 Mar 2004
Thomas Wayne R, Hales Belinda J, Smith Wendy-Anne
Abstract excerpt
T-cell responses constitute a central element of allergic disease and a model for studying Th1 and Th2 cytokine pathways. Most studies to date have used extracts of allergens which contain variable quantities of different allergens and non-allergenic antigens. Recombinant allergens provide the tools for studying the responses to allergens in a reproducible and dose-dependent manner and the different T-cell...
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