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Article

Properties of hepatitis C virus minigenome containing mutated 5'UTR region and luciferase transgene.

Acta virologica - 1 Jan 2010

Yang J, Lei Y F, An Q X, Yin W, Lu X, Ye L, Wei S H, Jia Z, Xu Z K

Abstract excerpt

UNLABELLED: Sequences at the 3'UTR of Hepatitis C virus (HCV) negative-strand (-)RNA play an important role in the initiation of positive-strand (+)RNA synthesis. However, the underlying mechanism in cellular context is still unclear. In this report, we designed several cDNA-based HCV-like minigenomes containing different mutations at the 5'UTR of (+)RNA. These (+)RNAs transcribed from the minigenomes in vitro...

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Share to 5' Untranslated Regions
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20545439
DOI: 10.4149/av_2010_02_105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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