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Article

Genetic organization and diversity of the 3' noncoding region of the hepatitis C virus genome.

Virology - 1 Sept 1996

Yamada N, Tanihara K, Takada A, Yorihuzi T, Tsutsumi M, Shimomura H, Tsuji T, Date T

Abstract excerpt

The 3' noncoding region (3' NCR) of the hepatitis C virus (HCV) genome contained in viral particles was analyzed by an RNA linker ligation followed by reverse transcription-polymerase chain reaction. Sequence analysis of the amplified fragment from four strains, including different genotypes 1b, 2b, 3a, and 3b indicated that the 3' NCR is composed of between 200 and 235 nts. The sequence of the 3' NCR consists of...

Topics

Base Sequence
Genetic Variation
Genome, Viral
Hepacivirus
Hepatitis C
Introns
Molecular Sequence Data
Nucleic Acid Conformation
Poly U
Polymerase Chain Reaction
RNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8806561
DOI: 10.1006/viro.1996.0476

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