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Article

Mutations of CARD11 but not TNFAIP3 may activate the NF-kappaB pathway in primary CNS lymphoma.

Acta neuropathologica - 1 Oct 2010

Montesinos-Rongen Manuel, Schmitz Roland, Brunn Anna, Gesk Stefan, Richter Julia, Hong Ke, Wiestler Otmar D, Siebert Reiner, Küppers Ralf, Deckert Martina

Abstract excerpt

Primary CNS lymphoma (PCNSL), the intracerebral subgroup of diffuse large B cell lymphoma (DLBCL), shows evidence for aberrant activation of the nuclear factor (NF)-kappaB pathway. In order to identify potential activators of the NF-kappaB complex, we analyzed the CARD11 and TNFAIP3 genes for the...

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Share to CARD Signaling Adaptor Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20544211
DOI: 10.1007/s00401-010-0709-7

Genes

TNFAIP3
CARD11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20544211-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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