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Article

Epigenetic silencing of multiple genes in primary CNS lymphoma

20 Jul 2006

Abstract excerpt

Epigenetic silencing of functionally important genes is important in the development of malignancies and is a source of potential markers for molecular detection. Primary central nervous system lymphoma (PCNSL) is an increasingly common tumor that has not been extensively examined for changes in promoter region methylation. We examined 14 tumor suppressor genes in 25 cases of PCNSL using methylation-specific PCR....

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Identifiers

PMID: 16858686
DOI: 10.1002/ijc.22124

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