Article
Slip-sliding away: serial changes and homoplasy in repeat number in the Drosophila yakuba homolog of human cancer susceptibility gene BRCA2.
PloS one - 8 Jun 2010
Bennett Sarah M, Mercer John M, Noor Mohamed A F
Abstract excerpt
Several recent studies have examined the function and evolution of a Drosophila homolog to the human breast cancer susceptibility gene BRCA2, named dmbrca2. We previously identified what appeared to be a recent expansion in the RAD51-binding BRC-repeat array in the ancestor of Drosophila yakuba. In this study, we examine patterns of variation and evolution of the dmbrca2 BRC-repeat array within D. yakuba and its...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
