Article
The biosynthetic pathway for aurofusarin in Fusarium graminearum reveals a close link between the naphthoquinones and naphthopyrones.
Molecular microbiology - 1 Aug 2006
Frandsen Rasmus J N, Nielsen Nikoline J, Maolanon Nicolai, Sørensen Jens C, Olsson Stefan, Nielsen John, Giese Henriette
Abstract excerpt
Fungal polyketide biosynthesis typically involves multiple enzymatic steps and the encoding genes are often found in gene clusters. A gene cluster containing PKS12, the polyketide synthase gene responsible for the synthesis of the pigment aurofusarin, was analysed by gene replacement using Agrobacterium tumefaciens-mediated transformation to determine the biosynthesis pathway of aurofusarin. Replacement of aurR1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.