Article
Methionine biosynthesis is essential for infection in the rice blast fungus Magnaporthe oryzae.
PloS one - 1 Jan 2015
Saint-Macary Marie Emmanuelle, Barbisan Crystel, Gagey Marie Josèphe, Frelin Océane, Beffa Roland, Lebrun Marc Henri, Droux Michel
Abstract excerpt
Methionine is a sulfur amino acid standing at the crossroads of several biosynthetic pathways. In fungi, the last step of methionine biosynthesis is catalyzed by a cobalamine-independent methionine synthase (Met6, EC 2.1.1.14). In the present work, we studied the role of Met6 in the infection process of the rice blast fungus, Magnaporthe oryzae. To this end MET6 null mutants were obtained by targeted gene...
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