Article

Plasma membrane folate transport in fungi and plants is mediated by members of the oligopeptide transporter (OPT) family

2025-06-24

Abstract excerpt

Folates are essential for all organisms. They are acquired either through de novo biosynthesis or from the diet. Yeast, fungi and plants make their own folates and it has not been clear if plasma membrane folate transporters exist in these organisms. Using a synthetic lethal screen in Saccharomyces cerevisiae we observed that deletions in a gene encoding the previously identified glutathione transporter, OPT1, w...

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Literature Corpus work: 7ca7a096-d02a-5610-91e4-27a988833c82
DOI: 10.1101/2025.06.23.661034

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