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Article

Genetic variations of interleukin-23R (1143A>G) and BPI (A645G), but not of NOD2, are associated with acute graft-versus-host disease after allogeneic transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Dec 2010

Wermke Martin, Maiwald Stefanie, Schmelz Renate, Thiede Christian, Schetelig Johannes, Ehninger Gerhard, Bornhäuser Martin, Wassmuth Ralf

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in genes of the immune system predict for aGVHD and mortality after allo-SCT. We investigated the effect of SNPs in the NOD2, BPI, and IL-23R genes on posttransplantation outcome in a cohort of 304 patients. NOD2 patient and donor genotype and BPI recipient genotype were not associated with the occurrence of aGVHD. However, IL-23R-SNP in the donor was correlated with less...

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Source

Identifiers

PMID: 20541026
DOI: 10.1016/j.bbmt.2010.06.001

Genes

BPI
NOD2
SCT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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