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Article

GSTP1 c.341C>T gene polymorphism increases the risk of oral squamous cell carcinoma.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Jul 2018

Rajesh Deepa, Balakrishna Sharath, Azeem Mohiyuddin S M, Suresh T N, Moideen Kutty A V

Abstract excerpt

Glutathione S Transferases (GST) are anti-oxidant enzymes involved in detoxification of cellular and exogenous carcinogens and oxidative products of reactive oxygen species. Genetic polymorphisms can attenuate the detoxification capacity of GST and consequently increase the susceptibility to carcinogenesis. There are eight classes of GST enzymes of which pi subtype is the predominant form expressed in the oral...

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Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29875076
DOI: 10.1016/j.mrgentox.2018.04.006

Genes

GSTP1

Variants

Provenance

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