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Article

The glutathione S-transferase P1 341C>T polymorphism and cancer risk: a meta-analysis of 28 case-control studies.

PloS one - 1 Jan 2013

Huang Sheng-xin, Wu Fei-xiang, Luo Min, Ma Liang, Gao Ke-feng, Li Jian, Wu Wen-juan, Huang Shan, Yang Qi, Liu Ke, Zhao Yin-nong, Li Le-qun

Abstract excerpt

BACKGROUND: GSTP1, which is one major group of the glutathione S-transferase family, plays an important role in the metabolism of carcinogens and toxins, reducing damage of DNA as a suppressor of carcinogenesis. The 341C>T polymorphism of the GSTP1 has been implicated in cancer risk through cutting down its metabolic detoxification activities. However, results from previous studies remain conflicting rather than...

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Identifiers

PMID: 23437223
DOI: 10.1371/journal.pone.0056722
PMCID: PMC3578943

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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