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Article

A novel method for tissue-specific RNAi rescue in Drosophila.

Nucleic acids research - 1 Jul 2009

Schulz Joachim G, David Guido, Hassan Bassem A

Abstract excerpt

Targeted gene silencing by RNA interference allows the study of gene function in plants and animals. In cell culture and small animal models, genetic screens can be performed--even tissue-specifically in Drosophila--with genome-wide RNAi libraries. However, a major problem with the use of RNAi approaches is the unavoidable false-positive error caused by off-target effects. Until now, this is minimized by...

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Identifiers

PMID: 19483100
DOI: 10.1093/nar/gkp450
PMCID: PMC2715260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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