Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[An RNA sequence determines the speed of its splitting by artificial ribonucleases].

Bioorganicheskaia khimiia - 1 Jan 2000

Tamkovich N V, Zenkov A N, Vlasov V V, Zenkova M A

Abstract excerpt

Phosphodiester bonds in RNA situated between similar nucleotides but in different sequences (context) were split under the action of artificial and natural ribonucleases with different speeds, and the reason for this phenomenon has not yet been fully revealed. In this study, the influence of one-nucleotide substitution on the sensitivity to splitting of the phosphodiester bonds in linear and structured RNA with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA, Messenger
Share to Base Sequence
Share to Oligoribonucleotides

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ribonucleases

Share to RNA, Fungal

Share to RNA, Transfer, Phe

Share to Substrate Specificity

Source

Identifiers

PMID: 20531481
DOI: 10.1134/s106816201002010x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[An RNA sequence determines the speed of its splitting by artificial ribonucleases].PMID 20531481Read ↗

[Nucleic acid syntheses and molecular recognition].Semantic proximity Read ↗

Construction of new ribozymes requiring short regulator oligonucleotides as a cofactor.Semantic proximity Read ↗

How RNase HI (Escherichia coli) promoted site-selective hydrolysis works on RNA in duplex with carba-LNA and LNA substituted antisense strands in an antisense strategy context?Semantic proximity Read ↗

Formation of the P1.1 pseudoknot is critical for both the cleavage activity and substrate specificity of an antigenomic trans-acting hepatitis delta ribozyme.Semantic proximity Read ↗

RNA secondary structure prediction with pseudoknots: Contribution of algorithm versus energy model.Semantic proximity Read ↗

Simultaneous targeted exchange of two nucleotides by single-stranded oligonucleotides clusters within a region of about fourteen nucleotides.Semantic proximity Read ↗

Secondary structure dimorphism and interconversion between hairpin and duplex form of oligoribonucleotides.Semantic proximity Read ↗

Isolation of new ribozymes from a large pool of random sequences [see comment].Semantic proximity Read ↗

Factors that contribute to efficient catalytic activity of a small Ca2+-dependent deoxyribozyme in relation to its RNA cleavage function.Semantic proximity Read ↗

Kinetic partitioning mechanism of HDV ribozyme folding.Semantic proximity Read ↗

Nucleotides -1 to -4 of hepatitis delta ribozyme substrate increase the specificity of ribozyme cleavage.Semantic proximity Read ↗

Mutational analysis of the antigenomic trans-acting delta ribozyme: the alterations of the middle nucleotides located on the P1 stem.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.