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Article

Influence of population stratification on population-based marker-disease association analysis.

Annals of human genetics - 1 Jul 2010

Li Tengfei, Li Zhaohai, Ying Zhiliang, Zhang Hong

Abstract excerpt

Population-based genetic association analysis may suffer from the failure to control for confounders such as population stratification (PS). There has been extensive study on the influence of PS on candidate gene-disease association analysis, but much less attention has been paid to its influence on marker-disease association analysis. In this paper, we focus on the Pearson chi(2) test and the trend test for...

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Identifiers

PMID: 20529080
DOI: 10.1111/j.1469-1809.2010.00588.x
PMCID: PMC2897957

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