Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Smoke exposure as a determinant of autoantibody titre in α₁-antitrypsin deficiency and COPD.

The European respiratory journal - 1 Jan 2011

Wood A M, de Pablo P, Buckley C D, Ahmad A, Stockley R A

Abstract excerpt

Liberation of elastin peptides from damaged lung may be a mechanism of autoimmune lung disease. Citrullination, and anti-citrullinated protein antibody formation occurs in smokers, but the role of smoking in autoantibody generation relevant to pulmonary disease is unclear. Anti-elastin, anti-cyclic citrullinated peptide (anti-CCP) and anti-mutated citrullinated vimentin (anti-MCV) antibodies were measured in 257...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha 1-Antitrypsin Deficiency
Share to Autoimmune Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Elastin

Share to Forced Expiratory Volume

Share to Lung Diseases

Share to Pulmonary Disease, Chronic Obstructive

Share to Smoking

Source

Identifiers

PMID: 20525711
DOI: 10.1183/09031936.00033710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Smoke exposure as a determinant of autoantibody titre in α₁-antitrypsin deficiency and COPD.PMID 20525711Read ↗

Anti-mutated citrullinated vimentin antibodies are increased in IPF patients.Semantic proximity Read ↗

COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype.Semantic proximity Read ↗

The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens.Semantic proximity Read ↗

Association of smoking with the constitution of the anti-cyclic citrullinated peptide response in the absence of HLA-DRB1 shared epitope alleles.Semantic proximity Read ↗

A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA–DR (shared epitope)–restricted immune reactions to autoantigens modified by citrullinationSemantic proximity Read ↗

Immune response in chronic obstructive pulmonary disease.Semantic proximity Read ↗

Smoking and Air Pollution as Pro-Inflammatory Triggers for the Development of Rheumatoid Arthritis.Semantic proximity Read ↗

Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles.Semantic proximity Read ↗

Gene-environmental interaction between smoking and shared epitope on the development of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.Semantic proximity Read ↗

Rheumatoid arthritis and smoking: putting the pieces together.Semantic proximity Read ↗

Anti–Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.