Article
Rheumatoid arthritis and smoking: putting the pieces together.
Arthritis research & therapy - 1 Jan 2009
Baka Zsuzsanna, Buzás Edit, Nagy György
Abstract excerpt
Besides atherosclerosis and lung cancer, smoking is considered to play a major role in the pathogenesis of autoimmune diseases. It has long been known that there is a connection between rheumatoid factor-positive rheumatoid arthritis and cigarette smoking. Recently, an important gene-environment interaction has been revealed; that is, carrying specific HLA-DRB1 alleles encoding the shared epitope and smoking...
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