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Article

Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles.

Annals of the rheumatic diseases - 1 Mar 2006

Linn-Rasker S P, van der Helm-van Mil A H M, van Gaalen F A, Kloppenburg M, de Vries R R P, le Cessie S, Breedveld F C, Toes R E M, Huizinga T W J

Abstract excerpt

OBJECTIVES: To study the gene-environment interaction of tobacco exposure and shared epitope on autoantibodies in patients with rheumatoid arthritis and undifferentiated arthritis. METHODS: From incident cases of arthritis (n = 1305), patients who did not fulfil any classification criteria (undif...

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Topics

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Share to Arthritis
Share to Arthritis, Rheumatoid
Share to Autoantibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Peptides, Cyclic

Share to Rheumatoid Factor

Source

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Identifiers

PMID: 16014670
DOI: 10.1136/ard.2005.041079
PMCID: PMC1798061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16014670-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles.PMID 16014670Read ↗

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