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Article

The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.

American journal of nephrology - 1 Jan 2010

Freedman Barry I, Edberg Jeffrey C, Comeau Mary E, Murea Mariana, Bowden Donald W, Divers Jasmin, Alarcón Graciela S, Brown Elizabeth E, McGwin Gerald, Kopp Jeffrey B, Winkler Cheryl A, Nelson George W, Illei Gabor, Petri Michelle, Ramsey-Goldman Rosalind, Reveille John D, Vilá Luis M, Langefeld Carl D, Kimberly Robert P

Abstract excerpt

BACKGROUND: African Americans (AA) disproportionately develop lupus nephritis (LN) relative to European Americans and familial clustering supports causative genes. Since MYH9 underlies approximately 40% of end-stage renal disease (ESRD) in AA, we tested for genetic association with LN. METHODS: Seven MYH9 single nucleotide polymorphisms (SNPs) and the E1 risk haplotype were tested for association with LN in three...

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Source

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Identifiers

PMID: 20523037
DOI: 10.1159/000314688
PMCID: PMC2914393

Genes

MYH9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.PMID 20523037Read ↗

Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.Semantic proximity Read ↗

Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans.Semantic proximity Read ↗

Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with albuminuria in hypertensive African Americans: the HyperGEN study.Semantic proximity Read ↗

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The spectrum of MYH9-associated nephropathy.Semantic proximity Read ↗

Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.Semantic proximity Read ↗

MYH9 is associated with nondiabetic end-stage renal disease in African Americans.Semantic proximity Read ↗

MYH9 and APOL1 gene polymorphisms and the risk of CKD in patients with lupus nephritis from an admixture population.Semantic proximity Read ↗

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