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Article

MYH9 and APOL1 gene polymorphisms and the risk of CKD in patients with lupus nephritis from an admixture population.

PloS one - 1 Jan 2014

Colares Vinícius Sardão, Titan Silvia Maria de Oliveira, Pereira Alexandre da Costa, Malafronte Patrícia, Cardena Mari M, Santos Sidney, Santos Paulo C, Fridman Cíntia, Barros Rui Toledo, Woronik Viktória

Abstract excerpt

MYH9 polymorphisms have been described to be associated with the risk of CKD in non-diabetic nephropathy, HIV nephropathy and FSGS. Predominating in black descendants, MHY9 genetic variants could partially explain the excess risk of CKD associated with African ancestry. However, recent data suggests that APOL1 gene co-segregate with MYH9, and could be the gene truly associated with CKD risk. In this study, we...

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Source

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Identifiers

PMID: 24658608
DOI: 10.1371/journal.pone.0087716
PMCID: PMC3962338

Genes

MYH9
APOL1
APOL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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MYH9 and APOL1 gene polymorphisms and the risk of CKD in patients with lupus nephritis from an admixture population.PMID 24658608Read ↗

Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.Semantic proximity Read ↗

Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans.Semantic proximity Read ↗

Epistatic role of the MYH9/APOL1 region on familial hematuria genes.Semantic proximity Read ↗

Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians.Semantic proximity Read ↗

Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene.Semantic proximity Read ↗

The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.Semantic proximity Read ↗

The MYH9/APOL1 region and chronic kidney disease in European-Americans.Semantic proximity Read ↗

Association between a MYH9 polymorphism (rs3752462) and renal function in the Spanish RENASTUR cohort.Semantic proximity Read ↗

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