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Article

Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes.

Journal of medical genetics - 1 Jun 2010

Wang Bing, Carter Rickey E, Jaffa Miran A, Nakerakanti Sashidhar, Lackland Daniel, Lopes-Virella Maria, Trojanowska Maria, Luttrell Louis M, Jaffa Ayad A

Abstract excerpt

BACKGROUND The evidence for genetic susceptibility in the pathogenesis of diabetic nephropathy is well recognised, but the genes involved remain to be identified. It is hypothesised that mutations within the gene encoding connective tissue growth factor (CTGF/CCN2) will increase the propensity of diabetic subjects to develop nephropathy. METHODS AND RESULTS Genomic screening was performed for single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20522428
DOI: 10.1136/jmg.2009.073098
PMCID: PMC3828650

Genes

CCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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