Article
Association of an Osteopontin gene promoter polymorphism with susceptibility to diabetic nephropathy in Asian Indians.
Clinica chimica acta; international journal of clinical chemistry - 9 Oct 2012
Cheema Balneek Singh, Iyengar Sreenivasa, Ahluwalia Tarunveer Singh, Kohli Harbir Singh, Sharma Rajni, Shah Viral N, Bhansali Anil, Sakhuja V, Khullar Madhu
Abstract excerpt
Genetic predisposition has been proposed to be a major determinant in the development of renal complications of diabetes. Osteopontin (OPN) has been suggested to be associated with renal diseases characterized by tubulointerstitial fibrosis and proteinuria. However, information on association of genetic polymorphisms in OPN with diabetic nephropathy is lacking. Thus, the present study was designed with the aim to...
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