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Article

Integrative Genome Comparison of Primary and Metastatic Melanomas

24 May 2010

Abstract excerpt

A cardinal feature of malignant melanoma is its metastatic propensity. An incomplete view of the genetic events driving metastatic progression has been a major barrier to rational development of effective therapeutics and prognostic diagnostics for melanoma patients. In this study, we conducted global genomic characterization of primary and metastatic melanomas to examine the genomic landscape associated with...

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Identifiers

PMID: 20520718
DOI: 10.1371/journal.pone.0010770

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