Article
Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profiling.
PloS one - 1 Jan 2013
Cifola Ingrid, Pietrelli Alessandro, Consolandi Clarissa, Severgnini Marco, Mangano Eleonora, Russo Vincenzo, De Bellis Gianluca, Battaglia Cristina
Abstract excerpt
Cutaneous malignant melanoma is the most fatal skin cancer and although improved comprehension of its pathogenic pathways allowed to realize some effective molecular targeted therapies, novel targets and drugs are still needed. Aiming to add genetic information potentially useful for novel targets discovery, we performed an extensive genomic characterization by whole-exome sequencing and SNP array profiling of...
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