Article
The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Dec 2010
Tang Sydney C W, Leung Violet T M, Chan Loretta Y Y, Wong Sunny S H, Chu Daniel W S, Leung Joseph C K, Ho Yiu Wing, Lai Kar Neng, Ma Lijun, Elbein Steven C, Bowden Donald W, Hicks Pamela J, Comeau Mary E, Langefeld Carl D, Freedman Barry I
Abstract excerpt
BACKGROUND: A single-nucleotide polymorphism (SNP), rs2268388, in the acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with susceptibility to type 2 diabetic nephropathy (T2DN) in Japanese and European-American populations. Whether this association also exists in Chinese patients is unclear. Attempts at replication in small Singaporean and Korean samples were not significant. METHODS: Eight ACACB...
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