Article
The N-acetyltransferase (NAT) gene: an early risk marker for diabetic nephropathy in Japanese type 2 diabetic patients?
Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 1994
Neugebauer S, Baba T, Watanabe T, Ishizaki T, Kurokawa K
Abstract excerpt
A point mutation in the N-acetyltransferase gene (NAT2) leads to the recessive trait for the slow acetylator phenotype, which is suggested to be associated with microalbuminuria in Type 1 diabetic patients. Our study was designed to elucidate whether the NAT2 gene polymorphism would be a marker for diabetic nephropathy. The genotype distribution was studied in Japanese Type 2 diabetic patients with established...
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