Article
N-acetyltransferase-2 polymorphism, smoking and type 1 diabetic nephropathy.
Pharmacogenetics - 1 Oct 1999
Korpinen E, Groop P H, Rautio A, Madácsy L, Reunanen A, Vaarala O, Akerblom H K
Abstract excerpt
The N-acetyltransferase (NAT2) polymorphism has been suggested to be related to diabetic microvascular complications. To study the distribution of NAT2 genotypes in Caucasian type 1 diabetic patients with and without diabetic nephropathy, 214 adult type 1 diabetic patients and 53 healthy individuals were genotyped by polymerase chain reaction-restriction fragment length polymorphism. In addition, 75 young type 1...
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