Article
Association of ACACB polymorphisms with obesity and diabetes.
Molecular genetics and metabolism - 1 Dec 2011
Riancho J A, Vázquez L, García-Pérez M A, Sainz J, Olmos J M, Hernández J L, Pérez-López J, Amado J A, Zarrabeitia M T, Cano A, Rodríguez-Rey J C
Abstract excerpt
Acetyl-CoA carboxylase beta, encoded by the ACAB gene, plays an important role in the oxidation of fatty acids. The aim of this study was to check the hypothesis that allelic variants of ACACB influence the risk of obesity and type 2 diabetes mellitus. Twenty five tagging single nucleotide polymorphisms (SNPs) capturing common variants of the ACACB gene were selected and analyzed in two cohorts including 1695...
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