Article
Cytokinesis proteins Tum and Pav have a nuclear role in Wnt regulation.
Journal of cell science - 1 Jul 2010
Jones Whitney M, Chao Anna T, Zavortink Michael, Saint Robert, Bejsovec Amy
Abstract excerpt
Wg/Wnt signals specify cell fates in both invertebrate and vertebrate embryos and maintain stem-cell populations in many adult tissues. Deregulation of the Wnt pathway can transform cells to a proliferative fate, leading to cancer. We have discovered that two Drosophila proteins that are crucial...
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