Article
Transcriptional repression by sumoylation of Epstein-Barr virus BZLF1 protein correlates with association of histone deacetylase.
The Journal of biological chemistry - 30 Jul 2010
Murata Takayuki, Hotta Naoe, Toyama Shigenori, Nakayama Sanae, Chiba Shigeki, Isomura Hiroki, Ohshima Takayuki, Kanda Teru, Tsurumi Tatsuya
Abstract excerpt
The transition from latent to lytic phases of the Epstein-Barr virus life cycle is triggered by expression of a viral transactivator, BZLF1, that then induces expression of the viral immediate-early and early genes. The BZLF1 protein is post-translationally modified by a small ubiquitin-related m...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
