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Article

Sulfadoxine-pyrimethamine impairs Plasmodium falciparum gametocyte infectivity and Anopheles mosquito survival.

International journal for parasitology - 15 Aug 2010

Kone Aminatou, van de Vegte-Bolmer Marga, Siebelink-Stoter Rianne, van Gemert Geert-Jan, Dara Antoine, Niangaly Hamidou, Luty Adrian, Doumbo Ogobara K, Sauerwein Robert, Djimde Abdoulaye A

Abstract excerpt

Sulfadoxine-pyrimethamine (SP) is currently the drug of choice for intermittent preventive treatment of Plasmodium falciparum both in pregnancy and infancy. A prolonged parasite clearance time conferred by dhfr and dhps mutations is believed to be responsible for increased gametocyte prevalence in SP treated individuals. However, using a direct feeding assay in Mali, we showed that gametocytes present in...

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Identifiers

PMID: 20515695
DOI: 10.1016/j.ijpara.2010.05.004
PMCID: PMC3744324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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