Male and Female Plasmodium falciparum Mature Gametocytes Show Different Responses to Antimalarial Drugs

Abstract excerpt

It is the mature gametocytes of Plasmodium that are solely responsible for parasite transmission from the mammalian host to the mosquito. They are therefore a logical target for transmission-blocking antimalarial interventions, which aim to break the cycle of reinfection and reduce the prevalence of malaria cases. Gametocytes, however, are not a homogeneous cell population. They are sexually dimorphic, and both...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Complement system in diseases
• Share to Malaria Research and Control
• Share to Mosquito-borne diseases and control