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Article

Assessing BRCA carrier probabilities in extended families.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jan 2006

Barcenas Carlos H, Hosain G M Monawar, Arun Banu, Zong Jihong, Zhou Xiaojun, Chen Jianfang, Cortada Jill M, Mills Gordon B, Tomlinson Gail E, Miller Alexander R, Strong Louise C, Amos Christopher I

Abstract excerpt

PURPOSE: Carrier prediction models estimate the probability that a person has a BRCA mutation. We evaluated the accuracy of the BOADICEA model and compared its performance with that of other models (BRCAPRO, Myriad I and II, Couch, and Manchester Scoring System). We also studied the effect of extended family information on risk estimation using BOADICEA. METHODS: We compared the area under receiver operating...

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Source

Identifiers

PMID: 16421416
DOI: 10.1200/JCO.2005.02.2368

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Assessing BRCA carrier probabilities in extended families.PMID 16421416Read ↗

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