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Article

Phenotypic robustness conferred by apparently redundant transcriptional enhancers.

Nature - 22 Jul 2010

Frankel Nicolás, Davis Gregory K, Vargas Diego, Wang Shu, Payre François, Stern David L

Abstract excerpt

Genes include cis-regulatory regions that contain transcriptional enhancers. Recent reports have shown that developmental genes often possess multiple discrete enhancer modules that drive transcription in similar spatio-temporal patterns: primary enhancers located near the basal promoter and secondary, or 'shadow', enhancers located at more remote positions. It has been proposed that the seemingly redundant...

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Identifiers

PMID: 20512118
DOI: 10.1038/nature09158
PMCID: PMC2909378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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