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Article

Two or four bristles: functional evolution of an enhancer of scute in Drosophilidae.

PLoS biology - 1 Nov 2006

Marcellini Sylvain, Simpson Pat

Abstract excerpt

Changes in cis-regulatory sequences are proposed to underlie much of morphological evolution. Yet, little is known about how such modifications translate into phenotypic differences. To address this problem, we focus on the dorsocentral bristles of Drosophilidae. In Drosophila melanogaster, development of these bristles depends on a cis-regulatory element, the dorsocentral enhancer, to activate scute in a cluster...

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Identifiers

PMID: 17105353
DOI: 10.1371/journal.pbio.0040386
PMCID: PMC1635746

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