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Article

A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila.

Current opinion in genetics & development - 1 Aug 2021

Kittelmann Sebastian, Preger-Ben Noon Ella, McGregor Alistair P, Frankel Nicolás

Abstract excerpt

The cuticle of insects is decorated with non-sensory hairs called trichomes. A few Drosophila species independently lost most of the dorso-lateral trichomes on first instar larvae. Genetic experiments revealed that this naked cuticle phenotype was caused by the evolution of enhancer function at the ovo/shavenbaby (ovo/svb) locus. Here we explore how this discovery catalyzed major new insights into morphological...

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PMID: 33529925
DOI: 10.1016/j.gde.2021.01.003

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