Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Morphological evolution through multiple cis-regulatory mutations at a single gene.

Nature - 2 Aug 2007

McGregor Alistair P, Orgogozo Virginie, Delon Isabelle, Zanet Jennifer, Srinivasan Dayalan G, Payre François, Stern David L

Abstract excerpt

One central, and yet unsolved, question in evolutionary biology is the relationship between the genetic variants segregating within species and the causes of morphological differences between species. The classic neo-darwinian view postulates that species differences result from the accumulation of small-effect changes at multiple loci. However, many examples support the possible role of larger abrupt changes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Drosophila

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Enhancer Elements, Genetic

Share to Gene Expression Regulation, Developmental

Share to Genes, Reporter

Share to Genetic Speciation

Share to Recombination, Genetic

Source

Identifiers

PMID: 17632547
DOI: 10.1038/nature05988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Morphological evolution through multiple cis-regulatory mutations at a single gene.PMID 17632547Read ↗

Cis-regulatory variation in the shavenbaby gene underlies intraspecific phenotypic variation, mirroring interspecific divergence in the same trait.Semantic proximity Read ↗

Conserved regulatory architecture underlies parallel genetic changes and convergent phenotypic evolution.Semantic proximity Read ↗

Morphological evolution caused by many subtle-effect substitutions in regulatory DNA.Semantic proximity Read ↗

Gene regulatory network architecture in different developmental contexts influences the genetic basis of morphological evolution.Semantic proximity Read ↗

The developmental genetics of microevolution.Semantic proximity Read ↗

A complex gene regulatory architecture underlies the development and evolution of cuticle morphology in Drosophila.Semantic proximity Read ↗

Distinct mechanisms decommission redundant enhancers to facilitate phenotypic evolution.Semantic proximity Read ↗

The loci of evolution: how predictable is genetic evolution?Semantic proximity Read ↗

A role of Ultrabithorax in morphological differences between Drosophila species.Semantic proximity Read ↗

Demystifying phenotypes: The comparative genomics of evo-devo.Semantic proximity Read ↗

Gene regulatory network co-option is sufficient to induce a morphological novelty in <i>Drosophila</i>Semantic proximity Read ↗

Experimental approaches to evaluate the contributions of candidate cis-regulatory mutations to phenotypic evolution.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.