Article
Super high-resolution single-molecule sequence-based typing of HLA class I alleles in HIV-1 infected individuals in Ghana.
PloS one - 1 Jan 2022
Nii-Trebi Nicholas I, Matsuoka Saori, Kawana-Tachikawa Ai, Bonney Evelyn Y, Abana Christopher Z, Ofori Sampson B, Mizutani Taketoshi, Ishizaka Aya, Shiino Teiichiro, Ohashi Jun, Naruse Taeko K, Kimura Akinori, Kiyono Hiroshi, Ishikawa Koichi, Ampofo William K, Matano Tetsuro
Abstract excerpt
Polymorphisms in human leukocyte antigen (HLA) class I loci are known to have a great impact on disease progression in HIV-1 infection. Prevailing HIV-1 subtypes and HLA genotype distribution are different all over the world, and the HIV-1 and host HLA interaction could be specific to individual areas. Data on the HIV-1 and HLA interaction have been accumulated in HIV-1 subtype B- and C-predominant populations...
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