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Article

Cysteine string protein-alpha prevents activity-dependent degeneration in GABAergic synapses.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 26 May 2010

García-Junco-Clemente Pablo, Cantero Gloria, Gómez-Sánchez Leonardo, Linares-Clemente Pedro, Martínez-López José A, Luján Rafael, Fernández-Chacón Rafael

Abstract excerpt

The continuous release of neurotransmitter could be seen to place a persistent burden on presynaptic proteins, one that could compromise nerve terminal function. This supposition and the molecular mechanisms that might protect highly active synapses merit investigation. In hippocampal cultures from knock-out mice lacking the presynaptic cochaperone cysteine string protein-alpha (CSP-alpha), we observe progressive...

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Identifiers

PMID: 20505105
DOI: 10.1523/JNEUROSCI.0924-10.2010
PMCID: PMC6632397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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