Article
Staying alive: dalmation mediated blocking of apoptosis is essential for tissue maintenance.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2010
Kerman Bilal E, Andrew Deborah J
Abstract excerpt
In an EMS screen for mutations disrupting tracheal development, we identified new alleles of the dalmation (dmt) gene, which had previously been shown to affect peripheral nervous system (PNS) development. Here, we demonstrate that dmt loss results in programmed cell death, disrupting PNS patterning and leading to large gaps in the salivary duct and trachea. Dmt loss results in increased expression of the...
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