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Article

UTX coordinates steroid hormone-mediated autophagy and cell death.

Nature communications - 1 Jan 2013

Denton Donna, Aung-Htut May T, Lorensuhewa Nirmal, Nicolson Shannon, Zhu Wenying, Mills Kathryn, Cakouros Dimitrios, Bergmann Andreas, Kumar Sharad

Abstract excerpt

Correct spatial and temporal induction of numerous cell type-specific genes during development requires regulated removal of the repressive histone H3 lysine 27 trimethylation (H3K27me3) modification. Here we show that the H3K27me3 demethylase dUTX is required for hormone-mediated transcriptional regulation of apoptosis and autophagy genes during ecdysone-regulated programmed cell death of Drosophila salivary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24336022
DOI: 10.1038/ncomms3916
PMCID: PMC3973156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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