Article
Mutations affecting neural survival in the zebrafish Danio rerio.
Development (Cambridge, England) - 1 Dec 1996
Abdelilah S, Mountcastle-Shah E, Harvey M, Solnica-Krezel L, Schier A F, Stemple D L, Malicki J, Neuhauss S C, Zwartkruis F, Stainier D Y, Rangini Z, Driever W
Abstract excerpt
Programmed cell death is a prominent feature of normal animal development. During neurogenesis, naturally occurring cell death is a mechanism to eliminate neurons that fail to make appropriate connections. To prevent accidental cell death, mechanisms that trigger programmed cell death, as well as the genetic components of the cell death program, are tightly controlled. In a large-scale mutagenesis screen for...
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