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Article

A helix replacement mechanism directs metavinculin functions.

PloS one - 19 May 2010

Rangarajan Erumbi S, Lee Jun Hyuck, Yogesha S D, Izard Tina

Abstract excerpt

Cells require distinct adhesion complexes to form contacts with their neighbors or the extracellular matrix, and vinculin links these complexes to the actin cytoskeleton. Metavinculin, an isoform of vinculin that harbors a unique 68-residue insert in its tail domain, has distinct actin bundling and oligomerization properties and plays essential roles in muscle development and homeostasis. Moreover, patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20502710
DOI: 10.1371/journal.pone.0010679
PMCID: PMC2873289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A helix replacement mechanism directs metavinculin functions.PMID 20502710Read ↗

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