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Article

Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2.

The Journal of biological chemistry - 20 May 2005

Kim Kyung-Tae, Choi Han-Ho, Steinmetz Michel O, Maco Bohumil, Kammerer Richard A, Ahn So Young, Kim Hak-Zoo, Lee Gyun Min, Koh Gou Young

Abstract excerpt

Angiopoietin-1 (Ang1) is an essential molecule for blood vessel formation; however, little is known about the structure-function relationships of Ang1 with its receptor, Tie2 (tyrosine kinase with immunoglobulin and epidermal growth factor homology domain-2'). In this study, we generated several...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15769741
DOI: 10.1074/jbc.M500292200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15769741-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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