Article
The association between copy number variations in glutathione S-transferase M1 and T1 and age-related cataract in a Han Chinese population.
Investigative ophthalmology & visual science - 1 Aug 2010
Zhou Jing, Hu Jianyan, Guan Huaijin
Abstract excerpt
PURPOSE: To determine the contribution of copy number variation (CNV) in glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) to the susceptibility to age-related cataract (ARC) and its subtypes in a Han Chinese population. METHODS: ARC cases (n = 279) and controls (n = 145) were included from a Han Chinese population-based prospective study. Quantitative RT-PCR and the DeltaCt method...
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