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Article

Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome.

The international journal of neuropsychopharmacology - 1 Jun 2011

Liu Zhong-Hua, Chuang De-Maw, Smith Carolyn Beebe

Abstract excerpt

As our understanding of the underlying defects in fragile X syndrome (FXS) increases so does the potential for development of treatments aimed at modulating the defects and ameliorating the constellation of symptoms seen in patients. Symptoms of FXS include cognitive disability, hyperactivity, autistic behaviour, seizures and learning deficits. Lithium is a drug used clinically to treat bipolar disorder, and it...

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Source

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Identifiers

PMID: 20497624
DOI: 10.1017/S1461145710000520
PMCID: PMC3102293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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