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Article

Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia.

Blood - 14 Jan 2010

Kanduri Meena, Cahill Nicola, Göransson Hanna, Enström Camilla, Ryan Fergus, Isaksson Anders, Rosenquist Richard

Abstract excerpt

Global hypomethylation and regional hypermethylation are well-known epigenetic features of cancer; however, in chronic lymphocytic leukemia (CLL), studies on genome-wide epigenetic modifications are limited. Here, we analyzed the global methylation profiles in CLL, by applying high-resolution methylation microarrays (27,578 CpG sites) to 23 CLL samples, belonging to the immunoglobulin heavy-chain variable (IGHV)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19897574
DOI: 10.1182/blood-2009-07-232868

Genes

ABI3
VHL
ADORA3
PRF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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